HBV Target gene Detail Information

> TBC1D4 Gene Search Result

Gene Information

Gene Name	TBC1D4
Gene ID	9882
Gene Full Name	TBC1 domain family member 4
Gene Alias	AS160; NIDDM5
Transcripts	ENSG00000136111
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	O60343
HGNC ID	HGNC:19165
VEGA ID	OTTHUMG00000017088
OMIM ID	612465
String ID	9606.ENSP00000366863
PharmGKB ID	PA38807

Target gene [TBC1D4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009957	chr13	9	5		14	View
1404552	chr13	35	2	3	40	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TBC1D4 expression and immune infiltrating cell level correlation result in HBV+ samples
TBC1D4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).