HIV Target gene Detail Information

> TBC1D20 Gene Search Result

Gene Information

Gene Name	TBC1D20
Gene ID	128637
Gene Full Name	TBC1 domain family member 20
Gene Alias	WARBM4; C20orf140
Transcripts	ENSG00000125875
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted membrane proteins
Uniport_ID	Q96BZ9
HGNC ID	HGNC:16133
VEGA ID	OTTHUMG00000031637
OMIM ID	611663
String ID	9606.ENSP00000346139
PharmGKB ID	PA25683

Target gene [TBC1D20] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003688	chr20	47	6	3	56	View
4012477	chr20	4	1		5	View
4012959	chr20	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TBC1D20 expression and immune infiltrating cell level correlation result in HIV+ samples
TBC1D20 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TBC1D20 expression and immune infiltrating cell level correlation result in HIV+ samples
TBC1D20 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).