HBV Target gene Detail Information

> TBC1D2 Gene Search Result


Gene Information
Gene Name TBC1D2
Gene ID 55357
Gene Full Name TBC1 domain family member 2
Gene Alias PARIS1; PARIS-1; TBC1D2A
Transcripts ENSG00000095383
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9BYX2
HGNC ID HGNC:18026
VEGA ID OTTHUMG00000020343
OMIM ID 609871
String ID 9606.ENSP00000481721
PharmGKB ID PA38280
Target gene [TBC1D2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007431 chr9 13 4 10 27 View
1009195 chr9 4 4 9 17 View
1009389 chr9 4 4 8 16 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TBC1D2 expression and immune infiltrating cell level correlation result in HBV+ samples
TBC1D2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).