HIV Target gene Detail Information

> TBC1D19 Gene Search Result


Gene Information
Gene Name TBC1D19
Gene ID 55296
Gene Full Name TBC1 domain family member 19
Transcripts ENSG00000109680
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear membrane;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8N5T2
HGNC ID HGNC:25624
VEGA ID OTTHUMG00000097797
String ID 9606.ENSP00000264866
PharmGKB ID PA134980991
Target gene [TBC1D19] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4004088 chr4 29 10 10 49 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of TBC1D19 expression and immune infiltrating cell level correlation result in HIV+ samples
TBC1D19 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of TBC1D19 expression and immune infiltrating cell level correlation result in HIV+ samples
TBC1D19 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).