HIV Target gene Detail Information

> TBC1D15 Gene Search Result

Gene Information

Gene Name	TBC1D15
Gene ID	64786
Gene Full Name	TBC1 domain family member 15
Gene Alias	RAB7-GAP
Transcripts	ENSG00000121749
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q8TC07
HGNC ID	HGNC:25694
VEGA ID	OTTHUMG00000158553
OMIM ID	612662
String ID	9606.ENSP00000448182
PharmGKB ID	PA134946839

Target gene [TBC1D15] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006582	chr12	24			24	View
4014597	chr12	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TBC1D15 expression and immune infiltrating cell level correlation result in HIV+ samples
TBC1D15 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TBC1D15 expression and immune infiltrating cell level correlation result in HIV+ samples
TBC1D15 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).