HIV Target gene Detail Information

> TBC1D10B Gene Search Result


Gene Information
Gene Name TBC1D10B
Gene ID 26000
Gene Full Name TBC1 domain family member 10B
Gene Alias EPI64B; FP2461
Transcripts ENSG00000169221
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q4KMP7
HGNC ID HGNC:24510
VEGA ID OTTHUMG00000132396
OMIM ID 613620
String ID 9606.ENSP00000386538
PharmGKB ID PA142670835
Target gene [TBC1D10B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4015296 chr16 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of TBC1D10B expression and immune infiltrating cell level correlation result in HIV+ samples
TBC1D10B expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of TBC1D10B expression and immune infiltrating cell level correlation result in HIV+ samples
TBC1D10B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).