HIV Target gene Detail Information

> TAPBP Gene Search Result

Gene Information

Gene Name	TAPBP
Gene ID	6892
Gene Full Name	TAP binding protein
Gene Alias	TPN; TAPA; TPSN; NGS17
Transcripts	ENSG00000206281
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O15533
HGNC ID	HGNC:11566
VEGA ID	OTTHUMG00000013076
OMIM ID	601962
String ID	9606.ENSP00000404833
PharmGKB ID	PA36331

Target gene [TAPBP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004014	chr6	24	27		51	View
4004572	chr6	40	2		42	View
4004604	chr6	40	2		42	View
4004785	chr6	39			39	View
4005640	chr6	31			31	View
4014513	chr6	2			2	View
4014514	chr6	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TAPBP expression and immune infiltrating cell level correlation result in HIV+ samples
TAPBP expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TAPBP expression and immune infiltrating cell level correlation result in HIV+ samples
TAPBP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).