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HIV Target gene Detail Information

> TAP2 Gene Search Result


Gene Information
Gene Name TAP2
Gene ID 6891
Gene Full Name transporter 2, ATP binding cassette subfamily B member
Gene Alias APT2; PSF2; ABC18; ABCB3; PSF-2; RING11; D6S217E
Transcripts ENSG00000225967
Virus HIV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;Nuclear speckles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID Q03519
HGNC ID HGNC:44
VEGA ID OTTHUMG00000012641
OMIM ID 170261
String ID 9606.ENSP00000364034
PharmGKB ID PA35022
Target gene [TAP2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002931 chr6 9 62 4 75 View
4005719 chr6 29 1 30 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of TAP2 expression and immune infiltrating cell level correlation result in HIV+ samples
TAP2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of TAP2 expression and immune infiltrating cell level correlation result in HIV+ samples
TAP2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).