HIV Target gene Detail Information

> TAP1 Gene Search Result

Gene Information

Gene Name	TAP1
Gene ID	6890
Gene Full Name	transporter 1, ATP binding cassette subfamily B member
Gene Alias	APT1; PSF1; ABC17; ABCB2; PSF-1; RING4; TAP1N; D6S114E; TAP1*0102N
Transcripts	ENSG00000232367
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centriolar satellite;Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q03518
HGNC ID	HGNC:43
VEGA ID	OTTHUMG00000012640
OMIM ID	170260
String ID	9606.ENSP00000346206
Drugbank ID	BE0003109
PharmGKB ID	PA35021

Target gene [TAP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005046	chr6	35	1		36	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
TAP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
TAP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).