HIV Target gene Detail Information

> TAF4B Gene Search Result

Gene Information

Gene Name	TAF4B
Gene ID	6875
Gene Full Name	TATA-box binding protein associated factor 4b
Gene Alias	SPGF13; TAF2C2; TAFII105
Transcripts	ENSG00000141384
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli fibrillar center;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q92750
HGNC ID	HGNC:11538
VEGA ID	OTTHUMG00000179429
OMIM ID	601689
String ID	9606.ENSP00000269142
PharmGKB ID	PA36313

Target gene [TAF4B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4014409	chr18	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TAF4B expression and immune infiltrating cell level correlation result in HIV+ samples
TAF4B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TAF4B expression and immune infiltrating cell level correlation result in HIV+ samples
TAF4B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).