HTLV1 Target gene Detail Information

> TADA2B Gene Search Result


Gene Information
Gene Name TADA2B
Gene ID 93624
Gene Full Name transcriptional adaptor 2B
Gene Alias ADA2B; ADA2(beta)
Transcripts ENSG00000173011
Virus HTLV1
Gene Type protein coding
HPA Location Info Nuclear speckles;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q86TJ2
HGNC ID HGNC:30781
VEGA ID OTTHUMG00000159983
OMIM ID 608790
String ID 9606.ENSP00000308022
PharmGKB ID PA165664556
Target gene [TADA2B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6003519 chr4 155 155 View
6017485 chr4 10 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of TADA2B expression and immune infiltrating cell level correlation result in HTLV1+ samples
TADA2B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).