HBV Target gene Detail Information

> TACC1 Gene Search Result


Gene Information
Gene Name TACC1
Gene ID 6867
Gene Full Name transforming acidic coiled-coil containing protein 1
Gene Alias Ga55
Transcripts ENSG00000147526
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID O75410
HGNC ID HGNC:11522
VEGA ID OTTHUMG00000164018
OMIM ID 605301
String ID 9606.ENSP00000321703
PharmGKB ID PA36299
Target gene [TACC1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1012912 chr8 3 3 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TACC1 expression and immune infiltrating cell level correlation result in HBV+ samples
TACC1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).