HIV Target gene Detail Information

> TAB2 Gene Search Result

Gene Information

Gene Name	TAB2
Gene ID	23118
Gene Full Name	TGF-beta activated kinase 1 (MAP3K7) binding protein 2
Gene Alias	CHTD2; TAB-2; MAP3K7IP2
Transcripts	ENSG00000055208
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9NYJ8
HGNC ID	HGNC:17075
VEGA ID	OTTHUMG00000015783
OMIM ID	605101
String ID	9606.ENSP00000356426
PharmGKB ID	PA30605

Target gene [TAB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002640	chr6	85	1		86	View
4003484	chr6	57	2	1	60	View
4003854	chr6	50	3		53	View
4004923	chr6	24	10	4	38	View
4005047	chr6	31	5		36	View
4005744	chr6	12	12	6	30	View
4006894	chr6	6	13	3	22	View
4007528	chr6	17	2		19	View
4007864	chr6	11	6		17	View
4007983	chr6	16	1		17	View
4008715	chr6	11	3		14	View
4010765	chr6	3	1	4	8	View
4011276	chr6	4	2	1	7	View
4011277	chr6	4	3		7	View
4012129	chr6	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TAB2 expression and immune infiltrating cell level correlation result in HIV+ samples
TAB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).