HIV Target gene Detail Information

> TAB1 Gene Search Result

Gene Information

Gene Name	TAB1
Gene ID	10454
Gene Full Name	TGF-beta activated kinase 1 (MAP3K7) binding protein 1
Gene Alias	3'-Tab1; MAP3K7IP1
Transcripts	ENSG00000100324
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q15750
HGNC ID	HGNC:18157
VEGA ID	OTTHUMG00000151102
OMIM ID	602615
String ID	9606.ENSP00000216160
Drugbank ID	BE0005871; BE0005824
PharmGKB ID	PA30604

Target gene [TAB1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006301	chr22	20	5	1	26	View
4010871	chr22	8			8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TAB1 expression and immune infiltrating cell level correlation result in HIV+ samples
TAB1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).