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HBV Target gene Detail Information

> SYTL2 Gene Search Result


Gene Information
Gene Name SYTL2
Gene ID 54843
Gene Full Name synaptotagmin like 2
Gene Alias EXO4; SLP2; SLP2A; SGA72M; CHR11SYT; PPP1R151
Transcripts ENSG00000137501
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;Nucleoplasm;Plasma membrane;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Transporters
Uniport_ID Q9HCH5
HGNC ID HGNC:15585
VEGA ID OTTHUMG00000166977
OMIM ID 612880
String ID 9606.ENSP00000318803
PharmGKB ID PA37985
Target gene [SYTL2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003123 chr11 17 83 64 164 View
1003387 chr11 8 87 43 138 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of SYTL2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SYTL2 expression: Low -> High
Lollipop of SYTL2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of SYTL2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SYTL2 expression and immune infiltrating cell level correlation result in HBV+ samples
SYTL2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).