HPV Target gene Detail Information

> SYT4 Gene Search Result

Gene Information

Gene Name	SYT4
Gene ID	6860
Gene Full Name	synaptotagmin 4
Gene Alias	HsT1192
Transcripts	ENSG00000132872
Virus	HPV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9H2B2
HGNC ID	HGNC:11512
VEGA ID	OTTHUMG00000132610
OMIM ID	600103
String ID	9606.ENSP00000255224
PharmGKB ID	PA36293

Target gene [SYT4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5402524	chr18				0	View
5403450	chr18	68	3		71	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of SYT4 expression and immune infiltrating cell level correlation result in HPV+ samples
SYT4 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of SYT4 expression and immune infiltrating cell level correlation result in HPV+ samples
SYT4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).