HPV Target gene Detail Information

> SYNPO2L Gene Search Result

Gene Information

Gene Name	SYNPO2L
Gene ID	79933
Gene Full Name	synaptopodin 2 like
Transcripts	ENSG00000166317
Virus	HPV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Cell Junctions;Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9H987
HGNC ID	HGNC:23532
VEGA ID	OTTHUMG00000018471
String ID	9606.ENSP00000378289
PharmGKB ID	PA134889033

Target gene [SYNPO2L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5400421	chr10	11	1		12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE138080 (GEO)	Cervical intraepithelial neoplasia	25	Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE138080
HeatMap of cell type fractions in all samples	Lollipop of SYNPO2L expression and immune infiltrating cell level correlation result in HPV+ samples
SYNPO2L expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of SYNPO2L expression and immune infiltrating cell level correlation result in HPV+ samples
SYNPO2L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).