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HBV Target gene Detail Information

> SYNE1 Gene Search Result


Gene Information
Gene Name SYNE1
Gene ID 23345
Gene Full Name spectrin repeat containing nuclear envelope protein 1
Gene Alias 8B; CPG2; ARCA1; EDMD4; KASH1; MYNE1; Nesp1; SCAR8; C6orf98; dJ45H2.2
Transcripts ENSG00000131018
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear membrane;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8NF91
HGNC ID HGNC:17089
VEGA ID OTTHUMG00000015841
OMIM ID 608441
String ID 9606.ENSP00000356224
PharmGKB ID PA134975331
Target gene [SYNE1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011745 chr6 6 2 8 View
1012374 chr6 4 3 7 View
1016072 chr6 1 1 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SYNE1 expression and immune infiltrating cell level correlation result in HBV+ samples
SYNE1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).