HBV Target gene Detail Information

> SYF2 Gene Search Result

Gene Information

Gene Name	SYF2
Gene ID	25949
Gene Full Name	SYF2 pre-mRNA splicing factor
Gene Alias	P29; CBPIN; NTC31; fSAP29
Transcripts	ENSG00000117614
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O95926
HGNC ID	HGNC:19824
VEGA ID	OTTHUMG00000043610
OMIM ID	607090
String ID	9606.ENSP00000236273
PharmGKB ID	PA142670853

Target gene [SYF2] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	12870011	L526M	P	D C	View
2	12870011	M550V	P	D C	View

Target gene [SYF2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1012015	chr1	8			8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SYF2 expression and immune infiltrating cell level correlation result in HBV+ samples
SYF2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: LIHC