HTLV1 Target gene Detail Information

> SYCP2L Gene Search Result

Gene Information

Gene Name	SYCP2L
Gene ID	221711
Gene Full Name	synaptonemal complex protein 2 like
Gene Alias	NO145; C6orf177; dJ62D2.1
Transcripts	ENSG00000153157
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q5T4T6
HGNC ID	HGNC:21537
VEGA ID	OTTHUMG00000014250
OMIM ID	616799
String ID	9606.ENSP00000283141
PharmGKB ID	PA162405118

Target gene [SYCP2L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6011552	chr6	16	10		26	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of SYCP2L expression and immune infiltrating cell level correlation result in HTLV1+ samples
SYCP2L expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of SYCP2L expression and immune infiltrating cell level correlation result in HTLV1+ samples
SYCP2L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).