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EBV Target gene Detail Information

> SUMO2 Gene Search Result


Gene Information
Gene Name SUMO2
Gene ID 6613
Gene Full Name small ubiquitin-like modifier 2
Gene Alias HSMT3; SMT3B; SUMO3; Smt3A; SMT3H2
Transcripts ENSG00000188612
Virus EBV
Gene Type protein coding
HPA Location Info Nuclear bodies;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID P61956
HGNC ID HGNC:11125
VEGA ID OTTHUMG00000179481
OMIM ID 603042
String ID 9606.ENSP00000405965
PharmGKB ID PA134914683
Target gene [SUMO2] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 20516063 K12R
BZLF1
 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE135644 (GEO) Gastric carcinoma 10 Gastric adenocarcinoma cell line AGS (5), Gastric adenocarcinoma cell line AGS (EBV+)(5)
GSE45919 (GEO) Infectious mononucleosis 24 Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO) Multiple sclerosis 32 Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of SUMO2 expression and immune infiltrating cell level correlation result in EBV+ samples
SUMO2 expression: Low -> High

> Dataset: GSE135644

HeatMap of cell type fractions in all samples Lollipop of SUMO2 expression and immune infiltrating cell level correlation result in EBV+ samples
SUMO2 expression: Low -> High

> Dataset: GSE45919

HeatMap of cell type fractions in all samples Lollipop of SUMO2 expression and immune infiltrating cell level correlation result in EBV+ samples
SUMO2 expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of SUMO2 expression and immune infiltrating cell level correlation result in EBV+ samples
SUMO2 expression: Low -> High

> Dataset: GSE58240

HeatMap of cell type fractions in all samples Lollipop of SUMO2 expression and immune infiltrating cell level correlation result in EBV+ samples
SUMO2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).