HIV Target gene Detail Information

> SUGT1 Gene Search Result

Gene Information

Gene Name	SUGT1
Gene ID	10910
Gene Full Name	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
Gene Alias	SGT1
Transcripts	ENSG00000165416
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9Y2Z0
HGNC ID	HGNC:16987
VEGA ID	OTTHUMG00000016977
OMIM ID	604098
String ID	9606.ENSP00000367208
PharmGKB ID	PA134880121

Target gene [SUGT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007084	chr13	20	1		21	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SUGT1 expression and immune infiltrating cell level correlation result in HIV+ samples
SUGT1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SUGT1 expression and immune infiltrating cell level correlation result in HIV+ samples
SUGT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).