HIV Target gene Detail Information

> SUFU Gene Search Result

Gene Information

Gene Name	SUFU
Gene ID	51684
Gene Full Name	SUFU negative regulator of hedgehog signaling
Gene Alias	SUFUH; JBTS32; SUFUXL; PRO1280
Transcripts	ENSG00000107882
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q9UMX1
HGNC ID	HGNC:16466
VEGA ID	OTTHUMG00000018966
OMIM ID	607035
String ID	9606.ENSP00000358918
PharmGKB ID	PA38146

Target gene [SUFU] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002530	chr10	80	9	1	90	View
4004671	chr10	13	23	5	41	View
4005220	chr10	32	1	2	35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SUFU expression and immune infiltrating cell level correlation result in HIV+ samples
SUFU expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).