HBV Target gene Detail Information

> SUCLG2 Gene Search Result


Gene Information
Gene Name SUCLG2
Gene ID 8801
Gene Full Name succinate-CoA ligase GDP-forming beta subunit
Gene Alias G-SCS; GBETA; GTPSCS
Transcripts ENSG00000172340
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;Plasma membrane;
HPA Protein Class Info Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q96I99
HGNC ID HGNC:11450
VEGA ID OTTHUMG00000158740
OMIM ID 603922
String ID 9606.ENSP00000419325
Drugbank ID BE0000355
PharmGKB ID PA36247
Target gene [SUCLG2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005125 chr3 42 10 9 61 View
1006891 chr3 26 5 2 33 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SUCLG2 expression and immune infiltrating cell level correlation result in HBV+ samples
SUCLG2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).