HBV Target gene Detail Information

> SUCLG1 Gene Search Result


Gene Information
Gene Name SUCLG1
Gene ID 8802
Gene Full Name succinate-CoA ligase alpha subunit
Gene Alias GALPHA; MTDPS9; SUCLA1
Transcripts ENSG00000163541
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;Cytosol;Plasma membrane;
HPA Protein Class Info Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID P53597
HGNC ID HGNC:11449
VEGA ID OTTHUMG00000130023
OMIM ID 611224
String ID 9606.ENSP00000377446
Drugbank ID BE0002255
PharmGKB ID PA36246
Target gene [SUCLG1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1015814 chr2 1 1 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SUCLG1 expression and immune infiltrating cell level correlation result in HBV+ samples
SUCLG1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).