HIV Target gene Detail Information

> STT3B Gene Search Result

Gene Information

Gene Name	STT3B
Gene ID	201595
Gene Full Name	STT3B, catalytic subunit of the oligosaccharyltransferase complex
Gene Alias	SIMP; CDG1X; STT3-B
Transcripts	ENSG00000163527
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins
Uniport_ID	Q8TCJ2
HGNC ID	HGNC:30611
VEGA ID	OTTHUMG00000130673
OMIM ID	608605
String ID	9606.ENSP00000295770
PharmGKB ID	PA143485625

Target gene [STT3B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003638	chr3	54	3		57	View
4006616	chr3	22	1		23	View
4010799	chr3	6	2		8	View
4013479	chr3	3			3	View
4014456	chr3	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of STT3B expression and immune infiltrating cell level correlation result in HIV+ samples
STT3B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of STT3B expression and immune infiltrating cell level correlation result in HIV+ samples
STT3B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).