HIV Target gene Detail Information

> STRN3 Gene Search Result

Gene Information

Gene Name	STRN3
Gene ID	29966
Gene Full Name	striatin 3
Gene Alias	SG2NA; S/G2NA; PPP2R6B
Transcripts	ENSG00000196792
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Actin filaments;Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q13033
HGNC ID	HGNC:15720
VEGA ID	OTTHUMG00000140201
OMIM ID	614766
String ID	9606.ENSP00000350071
PharmGKB ID	PA38394

Target gene [STRN3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001907	chr14	60	16	48	124	View
4013592	chr14	1	2		3	View
4016754	chr14				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of STRN3 expression and immune infiltrating cell level correlation result in HIV+ samples
STRN3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of STRN3 expression and immune infiltrating cell level correlation result in HIV+ samples
STRN3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).