HIV Target gene Detail Information

> STRN Gene Search Result

Gene Information

Gene Name	STRN
Gene ID	6801
Gene Full Name	striatin
Gene Alias	SG2NA; STRN1; PPP2R6A
Transcripts	ENSG00000115808
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins
Uniport_ID	O43815
HGNC ID	HGNC:11424
VEGA ID	OTTHUMG00000100959
OMIM ID	614765
String ID	9606.ENSP00000263918
PharmGKB ID	PA36224

Target gene [STRN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000833	chr2	261	7	1	269	View
4004890	chr15	38			38	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of STRN expression and immune infiltrating cell level correlation result in HIV+ samples
STRN expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of STRN expression and immune infiltrating cell level correlation result in HIV+ samples
STRN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).