HIV Target gene Detail Information

> STRADA Gene Search Result

Gene Information

Gene Name	STRADA
Gene ID	92335
Gene Full Name	STE20-related kinase adaptor alpha
Gene Alias	LYK5; PMSE; Stlk; STRAD; NY-BR-96; STRAD alpha
Transcripts	ENSG00000266173
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q7RTN6
HGNC ID	HGNC:30172
VEGA ID	OTTHUMG00000178908
OMIM ID	608626
String ID	9606.ENSP00000336655
PharmGKB ID	PA164726342

Target gene [STRADA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009357	chr17	11	1		12	View
4012259	chr17	3	2		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of STRADA expression and immune infiltrating cell level correlation result in HIV+ samples
STRADA expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of STRADA expression and immune infiltrating cell level correlation result in HIV+ samples
STRADA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).