HTLV1 Target gene Detail Information

> STRA6 Gene Search Result

Gene Information

Gene Name	STRA6
Gene ID	64220
Gene Full Name	stimulated by retinoic acid 6
Gene Alias	MCOPS9; MCOPCB8; PP14296
Transcripts	ENSG00000288257
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Gene Function	Oncogene
Uniport_ID	Q9BX79
HGNC ID	HGNC:30650
VEGA ID	OTTHUMG00000138998
OMIM ID	610745
String ID	9606.ENSP00000456609
Drugbank ID	BE0010167
PharmGKB ID	PA134956551

Target gene [STRA6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6013263	chr15	1	18	1	20	View
6016184	chr15	10	3		13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of STRA6 expression and immune infiltrating cell level correlation result in HTLV1+ samples
STRA6 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of STRA6 expression and immune infiltrating cell level correlation result in HTLV1+ samples
STRA6 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of STRA6 expression and immune infiltrating cell level correlation result in HTLV1+ samples
STRA6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).