HIV Target gene Detail Information

> STK38 Gene Search Result

Gene Information

Gene Name	STK38
Gene ID	11329
Gene Full Name	serine/threonine kinase 38
Gene Alias	NDR; NDR1
Transcripts	ENSG00000112079
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q15208
HGNC ID	HGNC:17847
VEGA ID	OTTHUMG00000014598
OMIM ID	606964
String ID	9606.ENSP00000229812
Drugbank ID	BE0009343
PharmGKB ID	PA38251

Target gene [STK38] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006200	chr6	6	19	1	26	View
4007524	chr6	15	3	1	19	View
4010068	chr6	10			10	View
4011502	chr6	6			6	View
4011780	chr6	6			6	View
4016391	chr6				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of STK38 expression and immune infiltrating cell level correlation result in HIV+ samples
STK38 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of STK38 expression and immune infiltrating cell level correlation result in HIV+ samples
STK38 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).