HBV Target gene Detail Information

> STK3 Gene Search Result

Gene Information

Gene Name	STK3
Gene ID	6788
Gene Full Name	serine/threonine kinase 3
Gene Alias	KRS1; MST2
Transcripts	ENSG00000104375
Virus	HBV
Gene Type	protein coding
HPA Location Info	Intermediate filaments;Rods & Rings;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q13188
HGNC ID	HGNC:11406
VEGA ID	OTTHUMG00000164651
OMIM ID	605030
String ID	9606.ENSP00000429744
Drugbank ID	BE0009338
Drug (Cytoscape Annotation)	Sunitinib Malate;Crizotinib;Bosutinib
PharmGKB ID	PA36213

Target gene [STK3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1012284	chr8	6	1		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of STK3 expression and immune infiltrating cell level correlation result in HBV+ samples
STK3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).