HBV Target gene Detail Information

> STK17A Gene Search Result

Gene Information

Gene Name	STK17A
Gene ID	9263
Gene Full Name	serine/threonine kinase 17a
Gene Alias	DRAK1
Transcripts	ENSG00000164543
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted membrane proteins
Uniport_ID	Q9UEE5
HGNC ID	HGNC:11395
VEGA ID	OTTHUMG00000022825
OMIM ID	604726
String ID	9606.ENSP00000319192
Drugbank ID	BE0009497; BE0009543
PharmGKB ID	PA36203

Target gene [STK17A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000160	chr7	1649	1899	1511	5059	View
1000292	chr7	113	1419	1471	3003	View
1402209	chr7	1649	1899	1511	5059	View
1402210	chr7	113	1419	1471	3003	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE114783 (GEO)	Chronic HBV (CHB) infection	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Hepatocellular carcinoma	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Liver cirrhosis	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783
HeatMap of cell type fractions in all samples	Lollipop of STK17A expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
STK17A expression: Low -> High
Lollipop of STK17A expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples	Lollipop of STK17A expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples


> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of STK17A expression and immune infiltrating cell level correlation result in HBV+ samples
STK17A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).