HIV Target gene Detail Information

> STIL Gene Search Result

Gene Information

Gene Name	STIL
Gene ID	6491
Gene Full Name	STIL, centriolar assembly protein
Gene Alias	SIL; MCPH7
Transcripts	ENSG00000123473
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q15468
HGNC ID	HGNC:10879
VEGA ID	OTTHUMG00000007851
OMIM ID	181590
String ID	9606.ENSP00000360944
PharmGKB ID	PA35780

Target gene [STIL] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007383	chr1	8	12	1	21	View
4011543	chr1	1		5	6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of STIL expression and immune infiltrating cell level correlation result in HIV+ samples
STIL expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of STIL expression and immune infiltrating cell level correlation result in HIV+ samples
STIL expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).