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HPV Target gene Detail Information

> STEAP2 Gene Search Result


Gene Information
Gene Name STEAP2
Gene ID 261729
Gene Full Name STEAP2 metalloreductase
Gene Alias STMP; IPCA1; PUMPCn; STAMP1; PCANAP1
Transcripts ENSG00000157214
Virus HPV
Gene Type protein coding
HPA Location Info Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID Q8NFT2
HGNC ID HGNC:17885
VEGA ID OTTHUMG00000023341
OMIM ID 605094
String ID 9606.ENSP00000378119
PharmGKB ID PA38473
Target gene [STEAP2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5300511 chr7 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of STEAP2 expression and immune infiltrating cell level correlation result in HPV+ samples
STEAP2 expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of STEAP2 expression and immune infiltrating cell level correlation result in HPV+ samples
STEAP2 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of STEAP2 expression and immune infiltrating cell level correlation result in HPV+ samples
STEAP2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).