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HIV Target gene Detail Information

> STAT5B Gene Search Result


Gene Information
Gene Name STAT5B
Gene ID 6777
Gene Full Name signal transducer and activator of transcription 5B
Gene Alias STAT5
Transcripts ENSG00000173757
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID P51692
HGNC ID HGNC:11367
VEGA ID OTTHUMG00000150724
OMIM ID 604260
String ID 9606.ENSP00000293328
Drugbank ID BE0000891
PharmGKB ID PA36186
Target gene [STAT5B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000047 chr17 158 773 713 1644 View
4000142 chr17 174 436 301 911 View
4000881 chr17 79 112 64 255 View
4001303 chr17 161 17 3 181 View
4001361 chr17 22 77 75 174 View
4001429 chr17 16 77 74 167 View
4001441 chr17 13 77 74 164 View
4001922 chr17 36 52 35 123 View
4001991 chr17 28 87 4 119 View
4002012 chr17 28 86 4 118 View
4002125 chr17 23 84 4 111 View
4002126 chr17 23 84 4 111 View
4002192 chr17 20 83 4 107 View
4002209 chr17 19 83 4 106 View
4002210 chr17 19 83 4 106 View
4002528 chr17 36 19 34 89 View
4002917 chr17 72 3 75 View
4003167 chr17 32 34 2 68 View
4003331 chr17 16 29 19 64 View
4003966 chr17 38 10 3 51 View
4004128 chr17 45 4 49 View
4004529 chr17 32 10 1 43 View
4004608 chr17 38 4 42 View
4004609 chr17 38 4 42 View
4005529 chr17 21 9 1 31 View
4006027 chr17 24 3 27 View
4006289 chr17 6 13 7 26 View
4007593 chr17 1 17 18 View
4007731 chr17 10 6 2 18 View
4008074 chr17 8 6 2 16 View
4009102 chr17 9 3 12 View
4009355 chr17 1 9 2 12 View
4009380 chr17 12 12 View
4010041 chr17 10 10 View
4010143 chr17 9 9 View
4010918 chr17 4 4 8 View
4010919 chr17 4 4 8 View
4010921 chr17 4 4 8 View
4010923 chr17 4 4 8 View
4010924 chr17 4 4 8 View
4010925 chr17 4 4 8 View
4010926 chr17 4 4 8 View
4010927 chr17 4 4 8 View
4010928 chr17 4 4 8 View
4010929 chr17 4 4 8 View
4010930 chr17 4 4 8 View
4010931 chr17 8 8 View
4010932 chr17 8 8 View
4011063 chr17 7 7 View
4011373 chr17 2 5 7 View
4011589 chr17 5 1 6 View
4011990 chr17 5 1 6 View
4013170 chr17 4 4 View
4013311 chr17 3 1 4 View
4014156 chr17 2 2 View
4014402 chr17 2 2 View
4014919 chr17 2 2 View
4015632 chr17 1 1 View
4015750 chr17 1 1 View
4100007 chr17 17 83 4 104 View
4100057 chr17 33 4 37 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of STAT5B expression and immune infiltrating cell level correlation result in HIV+ samples
STAT5B expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of STAT5B expression and immune infiltrating cell level correlation result in HIV+ samples
STAT5B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).