HBV Target gene Detail Information

> STAT1 Gene Search Result

Gene Information

Gene Name	STAT1
Gene ID	6772
Gene Full Name	signal transducer and activator of transcription 1
Gene Alias	CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
Transcripts	ENSG00000115415
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	P42224
HGNC ID	HGNC:11362
VEGA ID	OTTHUMG00000132699
OMIM ID	600555
String ID	9606.ENSP00000354394
PharmGKB ID	PA36183

Target gene [STAT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006926	chr2	32			32	View
1006927	chr2	32			32	View
1007547	chr2	22	4		26	View
1011265	chr2	9			9	View
1018295	chr2				0	View
1403455	chr2	9			9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of STAT1 expression and immune infiltrating cell level correlation result in HBV+ samples
STAT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).