HBV Target gene Detail Information

> ST8SIA1 Gene Search Result

Gene Information

Gene Name	ST8SIA1
Gene ID	6489
Gene Full Name	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Gene Alias	GD3S; SIAT8; SIAT8A; SIAT8-A; ST8SiaI
Transcripts	ENSG00000111728
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q92185
HGNC ID	HGNC:10869
VEGA ID	OTTHUMG00000169098
OMIM ID	601123
String ID	9606.ENSP00000379353
PharmGKB ID	PA35770

Target gene [ST8SIA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001478	chr12	128	162	400	690	View
1003111	chr12	96	5	64	165	View
1003112	chr12	96	5	64	165	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ST8SIA1 expression and immune infiltrating cell level correlation result in HBV+ samples
ST8SIA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).