HBV Target gene Detail Information

> ST6GAL2 Gene Search Result


Gene Information
Gene Name ST6GAL2
Gene ID 84620
Gene Full Name ST6 beta-galactoside alpha-2,6-sialyltransferase 2
Gene Alias SIAT2; ST6GalII
Transcripts ENSG00000144057
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoli fibrillar center;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q96JF0
HGNC ID HGNC:10861
VEGA ID OTTHUMG00000130923
OMIM ID 608472
String ID 9606.ENSP00000386942
PharmGKB ID PA35763
Target gene [ST6GAL2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009983 chr2 14 14 View
1011580 chr2 8 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ST6GAL2 expression and immune infiltrating cell level correlation result in HBV+ samples
ST6GAL2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).