HIV Target gene Detail Information

> ST3GAL6 Gene Search Result

Gene Information

Gene Name	ST3GAL6
Gene ID	10402
Gene Full Name	ST3 beta-galactoside alpha-2,3-sialyltransferase 6
Gene Alias	SIAT10; ST3GALVI
Transcripts	ENSG00000064225
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9Y274
HGNC ID	HGNC:18080
VEGA ID	OTTHUMG00000159047
OMIM ID	607156
String ID	9606.ENSP00000480884
PharmGKB ID	PA134958548

Target gene [ST3GAL6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011397	chr3	7			7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ST3GAL6 expression and immune infiltrating cell level correlation result in HIV+ samples
ST3GAL6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ST3GAL6 expression and immune infiltrating cell level correlation result in HIV+ samples
ST3GAL6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).