HIV Target gene Detail Information

> ST3GAL5 Gene Search Result


Gene Information
Gene Name ST3GAL5
Gene ID 8869
Gene Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 5
Gene Alias SATI; SIAT9; SPDRS; ST3GalV; SIATGM3S; ST3Gal V
Transcripts ENSG00000115525
Virus HIV
Gene Type protein coding
HPA Location Info Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9UNP4
HGNC ID HGNC:10872
VEGA ID OTTHUMG00000130171
OMIM ID 604402
String ID 9606.ENSP00000366549
Drugbank ID BE0004604
PharmGKB ID PA35773
Target gene [ST3GAL5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000839 chr2 80 77 111 268 View
4014008 chr2 3 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ST3GAL5 expression and immune infiltrating cell level correlation result in HIV+ samples
ST3GAL5 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ST3GAL5 expression and immune infiltrating cell level correlation result in HIV+ samples
ST3GAL5 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).