HBV Target gene Detail Information

> ST3GAL4 Gene Search Result


Gene Information
Gene Name ST3GAL4
Gene ID 6484
Gene Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 4
Gene Alias STZ; SAT3; ST-4; CGS23; SIAT4; NANTA3; SIAT4C; ST3GalIV; ST3GalA.2; gal-NAc6S
Transcripts ENSG00000110080
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q11206
HGNC ID HGNC:10864
VEGA ID OTTHUMG00000165830
OMIM ID 104240
String ID 9606.ENSP00000436047
PharmGKB ID PA35766
Target gene [ST3GAL4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006667 chr11 35 35 View
1401347 chr11 35 35 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ST3GAL4 expression and immune infiltrating cell level correlation result in HBV+ samples
ST3GAL4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).