HIV Target gene Detail Information

> SRSF3 Gene Search Result

Gene Information

Gene Name	SRSF3
Gene ID	6428
Gene Full Name	serine and arginine rich splicing factor 3
Gene Alias	SFRS3; SRp20
Transcripts	ENSG00000112081
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	P84103
HGNC ID	HGNC:10785
VEGA ID	OTTHUMG00000014599
OMIM ID	603364
String ID	9606.ENSP00000362820
PharmGKB ID	PA35701

Target gene [SRSF3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001454	chr6	152	10	1	163	View
4006973	chr6	12	9		21	View
4006974	chr6	12	9		21	View
4006975	chr6	12	9		21	View
4006976	chr6	12	9		21	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SRSF3 expression and immune infiltrating cell level correlation result in HIV+ samples
SRSF3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).