HIV Target gene Detail Information

> SRSF1 Gene Search Result

Gene Information

Gene Name	SRSF1
Gene ID	6426
Gene Full Name	serine and arginine rich splicing factor 1
Gene Alias	ASF; SF2; SFRS1; SF2p33; SRp30a
Transcripts	ENSG00000136450
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q07955
HGNC ID	HGNC:10780
VEGA ID	OTTHUMG00000178781
OMIM ID	600812
String ID	9606.ENSP00000258962
Drugbank ID	BE0009142; BE0009139
PharmGKB ID	PA35696

Target gene [SRSF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002769	chr17	78	3		81	View
4002990	chr17	71	2		73	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SRSF1 expression and immune infiltrating cell level correlation result in HIV+ samples
SRSF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).