HIV Target gene Detail Information

> SRP68 Gene Search Result

Gene Information

Gene Name	SRP68
Gene ID	6730
Gene Full Name	signal recognition particle 68
Transcripts	ENSG00000167881
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Transporters
Uniport_ID	Q9UHB9
HGNC ID	HGNC:11302
VEGA ID	OTTHUMG00000180054
OMIM ID	604858
String ID	9606.ENSP00000312066
PharmGKB ID	PA36126

Target gene [SRP68] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000657	chr17	296	9	24	329	View
4003230	chr17	66			66	View
4003964	chr17	23	18	10	51	View
4005358	chr17	33			33	View
4008006	chr17	15	2		17	View
4009178	chr17	11	1		12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SRP68 expression and immune infiltrating cell level correlation result in HIV+ samples
SRP68 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SRP68 expression and immune infiltrating cell level correlation result in HIV+ samples
SRP68 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).