HBV Target gene Detail Information

> SRGAP3 Gene Search Result

Gene Information

Gene Name	SRGAP3
Gene ID	9901
Gene Full Name	SLIT-ROBO Rho GTPase activating protein 3
Gene Alias	WRP; MEGAP; SRGAP2; ARHGAP14
Transcripts	ENSG00000196220
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	O43295
HGNC ID	HGNC:19744
VEGA ID	OTTHUMG00000090589
OMIM ID	606525
String ID	9606.ENSP00000373347
PharmGKB ID	PA134935463

Target gene [SRGAP3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013344	chr3	4	1		5	View
1404305	chr3	7	1	11	19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SRGAP3 expression and immune infiltrating cell level correlation result in HBV+ samples
SRGAP3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).