HBV Target gene Detail Information

> SRGAP1 Gene Search Result

Gene Information

Gene Name	SRGAP1
Gene ID	57522
Gene Full Name	SLIT-ROBO Rho GTPase activating protein 1
Gene Alias	NMTC2; ARHGAP13
Transcripts	ENSG00000196935
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q7Z6B7
HGNC ID	HGNC:17382
VEGA ID	OTTHUMG00000168750
OMIM ID	606523
String ID	9606.ENSP00000347198
PharmGKB ID	PA134887956

Target gene [SRGAP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011025	chr12	4	5	1	10	View
1011936	chr12	8			8	View
1013010	chr12	4	1	1	6	View
1400492	chr12	5	2		7	View
1404275	chr12	30	3		33	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SRGAP1 expression and immune infiltrating cell level correlation result in HBV+ samples
SRGAP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).