HIV Target gene Detail Information

> SREBF2 Gene Search Result


Gene Information
Gene Name SREBF2
Gene ID 6721
Gene Full Name sterol regulatory element binding transcription factor 2
Gene Alias SREBP2; bHLHd2; SREBP-2
Transcripts ENSG00000198911
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;Endoplasmic reticulum;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors
Uniport_ID Q12772
HGNC ID HGNC:11290
VEGA ID OTTHUMG00000151261
OMIM ID 600481
String ID 9606.ENSP00000354476
PharmGKB ID PA336
Target gene [SREBF2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002950 chr22 71 3 74 View
4003301 chr22 58 6 64 View
4004375 chr22 38 7 45 View
4004961 chr22 33 4 37 View
4005410 chr22 27 6 33 View
4009845 chr22 7 3 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of SREBF2 expression and immune infiltrating cell level correlation result in HIV+ samples
SREBF2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).