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HBV Target gene Detail Information

> SRCAP Gene Search Result


Gene Information
Gene Name SRCAP
Gene ID 10847
Gene Full Name Snf2 related CREBBP activator protein
Gene Alias EAF1; FLHS; SWR1; DOMO1
Transcripts ENSG00000080603
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Golgi apparatus;Nuclear bodies;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q6ZRS2
HGNC ID HGNC:16974
VEGA ID OTTHUMG00000132393
OMIM ID 611421
String ID 9606.ENSP00000262518
PharmGKB ID PA162404706
Target gene [SRCAP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010936 chr16 10 10 View
1401626 chr16 10 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of SRCAP expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SRCAP expression: Low -> High
Lollipop of SRCAP expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of SRCAP expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SRCAP expression and immune infiltrating cell level correlation result in HBV+ samples
SRCAP expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).