HBV Target gene Detail Information

> SPTLC3 Gene Search Result

Gene Information

Gene Name	SPTLC3
Gene ID	55304
Gene Full Name	serine palmitoyltransferase long chain base subunit 3
Gene Alias	LCB3; SPT3; LCB 3; LCB2B; SPT 3; hLCB2b; SPTLC2L; C20orf38; dJ718P11; dJ718P11.1
Transcripts	ENSG00000172296
Virus	HBV
Gene Type	protein coding
HPA Location Info	Microtubules;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9NUV7
HGNC ID	HGNC:16253
VEGA ID	OTTHUMG00000031899
OMIM ID	611120
String ID	9606.ENSP00000381968
Drugbank ID	BE0002172
PharmGKB ID	PA162404677

Target gene [SPTLC3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005292	chr20	8	15	34	57	View
1013513	chr20	5			5	View
1014976	chr20	3			3	View
1019568	chr20				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SPTLC3 expression and immune infiltrating cell level correlation result in HBV+ samples
SPTLC3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).